This course will focus on the applications of magnetic resonance in chemistry, chemical biology, biochemistry, and biophysics. Hands-on projects that deal with NMR chemical shift assignments of biological macromolecules such as proteins and oligonucleotides (DNA/RNA) form the core of the class. Related topics such as magnetic resonance imaging (MRI), NMR in metabolomics and drug discovery, dynamic nuclear polarization (DNP), and electron paramagnetic resonance (EPR) will also be discussed. Concurrent lab sessions will solve problems using magnetic resonancemethods to make the experience more practical and useful.
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