The purpose of this course is to expose students to current topics in chemical genomics, chemical proteomics and related -omics sciences. The course will cover cutting-edge genomic and proteomic experimental methods and platforms as well as explore the rapidly expanding role that chemistry plays within these research areas. As an advanced biochemistry elective, students will further their knowledge of gene and protein function, biomolecular chemical modifications, cellular signaling, and drug discovery. By the end of the course, students will have: 1) a detailed understanding of the history and future direction of chemical genomics and proteomics; 2) an appreciation for the role that chemical probes, inhibitors, and small molecule libraries play in genomic and proteomic research; 3) an understanding of how to apply chemical genomics and proteomics platforms to answer specific and appropriate scientific questions; and 4) the analytical and computational skills necessary to interpret and analyze large genomic and proteomic datasets.
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